Human Biology:孕妇经济地位差异影响婴儿健康


这项研究最近发表在American Journal of Human Biology杂志上,是第一项研究评估了婴儿皮质醇水平与婴儿母亲怀孕期间社会经济地位之间的关系。

目前,已经有几项针对青少年皮质醇水平和成人社会经济地位关系的研究,但这是第一次分析孕妇和婴儿之间的这种关系,研究报告的作者Zaneta Thayer博士说:这些结果对于健康差距如何可以跨代遗传,提供了新的见解。



其他问题包括:你有没有亲自被迫购买更便宜的食物?你有没有忍受寒冷,以节省取暖费用?你有没有利用食物银行或食物补助,因为你没有足够的钱买食物?你有没有新鲜的水果或蔬菜?你的衣服或钱是不是从社区组织如Salvation Army等获得?



Early origins of health disparities: Material deprivation predicts maternal evening cortisol in pregnancy and offspring cortisol reactivity in the first few weeks of life

Objectives:Maternal hypothalamic pituitary adrenal-axis function regulates production of the stress hormone cortisol, which during pregnancy can cross the placenta and have lasting impacts on fetal growth and development. This article provides a preliminary test of the hypothesis that a woman’s socioeconomic status (SES) predicts her cortisol during pregnancy and her offspring’s cortisol during the early postnatal period among an ethnically diverse sample in Auckland, New Zealand to evaluate whether differences in cortisol contribute to the intergenerational inheritance of health disparities within this population. Methods:Maternal saliva samples were collected at waking and prior to sleep on 2 days in late pregnancy (34–36 weeks gestation; N = 55), and a subset of offspring saliva was collected before (N = 48) and 20 min after a standard vaccination at 6 weeks of age (N = 19). SES was quantified using a locally validated index of material deprivation, the NZ Deprivation Index for individuals (NZiDep). Results:We found that, after controlling for ethnicity and other covariates, women with higher NZiDep scores had significantly higher evening but similar morning cortisol, consistent with a pattern of chronic strain. Infants of women reporting greater material deprivation had elevated cortisol response to vaccination. Conclusions:These findings suggest that maternal SES experience impacts maternal cortisol in pregnancy and offspring cortisol reactivity soon after birth, with potential long-term effects on offspring biology and health. Additional research is needed to clarify how biological and behavioral factors in both the prenatal and postnatal period facilitate this relationship.